🧬 HoloGene

AI Agent System for Gene Functional Annotation and Homology Analysis.

How to Use HoloGene

A simple step-by-step guide to extract, annotate, and analyze gene data from NCBI GenBank with our AI-powered platform

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Step 1: Choose Your Input Method

Start your analysis by selecting either a GenBank accession number for direct genome access or an organism name for AI-assisted genome discovery.

Example: NC_009089.1 or Clostridium difficile
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Step 2: AI-Powered Genome Recommendation

Our advanced AI Agent leverages neural network architectures to query external databases like KEGG, identifying the most relevant reference genomes for your analysis.

Neural Networks • Smart Filtering • Quality Scoring
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Step 3: Automated Data Extraction

HoloGene automatically extracts comprehensive gene information from NCBI GenBank, including locus tags, coding sequences, protein IDs, EC numbers, and functional annotations.

Performance: ~10 minutes for 10 genomes
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Step 4: Results & Reports

Receive detailed gene datasets and homology mapping reports in structured formats. Our intelligent reporting system generates publication-ready tables with clear functional annotations.

CSV tables • Interactive visualizations • Export options
🚀 Start Your Analysis

🟢 AI Agent Online | Ready for intelligent genome analysis

Our Team

Dr. Zheng Chen

Dr. Zheng Chen

University of Osaka, Japan

Xihao Piao

Xihao Piao

University of Osaka, Japan

Ziwei Yang

Ziwei Yang

Kyoto University, Japan

Dr. Dafang Zhao

Dr. Dafang Zhao

University of Osaka, Japan

Dr. Peng Gao

Dr. Peng Gao

Tokyo University, Japan

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